What will happen to DNA samples if the electrodes in an agarose gel are reversed?

When the electrodes in an agarose gel are reversed, the DNA will migrate in the opposite direction compared to its normal movement. DNA molecules are negatively charged due to their phosphate backbone, and in a typical setup, they migrate towards the positive electrode (anode). If the electrodes are reversed, the negatively charged DNA will instead move towards the negative electrode (cathode), which is typically at the top of the gel. As a result, the DNA can be observed to "run out" from the top of the gel, indicating that its usual path has been altered due to the reversal of the electric field within the gel.